Blume, Jeffrey
Associate Professor:
Biostatistics; Community Health
Phone: +1 401 863 9968
jblume@stat.brown.edu
Professor Blume's research focuses on three distinct areas: (1) likelihood methods for measuring statistical evidence, (2) methodology for analyzing and interpreting Receiver Operating Characteristic (ROC) curves, (3) the design, conduct and analysis of Clinical Trials, especially sequential Trials, of diagnostic and screening technologies. He also has interest in applying ROC curve concepts to Biomarkers for the prediction of disease.
Professor Blume is a founder and the Chief Scientific Officer (CSO) for a newly formed Biostatistics consulting company: Analytical Edge Inc. (www.analyticaledge.com). Analytical Edge offers cutting edge expertise and software in likelihood methods for measuring the strength of statistical evidence.
Biography
Dr. Blume is an Associate Professor in the Center for Statistical Sciences at Brown University. Dr. Blume received his Ph.D. in Biostatistics from the Johns Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials. Dr. Blume is a founder and the Chief Scientific Officer (CSO) of Analytical Edge Inc (www.analyticaledge.com).
Dr. Blume is also the Deputy Direction of the Biostatistics and Data management center for the American College of Radiology Imaging Network (ACRIN), a NCI funded cooperative group that specializes in clinical trials evaluating new medical imaging technology (www.acrin.org). He is also the lead statistician on six ACRIN trials that range in size and scope: a retrospective reader study (ACRIN 6662: 24 cases and 16 readers), a cohort study of women with stage III breast cancer (ACRIN 6657; 244 participants anticipated), and a large prospective screening trial of whole breast ultrasound (ACRIN 6666; 2808 participants anticipated).
Interests
For more information, please contact Professor Blume.
Degrees
PhD, Johns Hopkins School of Public Health, 1999
Awards
NIH loan repayment program recipient, 2003-2005, 2005-2007
(Competitive award for researchers in cancer clinical trials)
ACRIN Certificate of Outstanding Contribution, 2004
(American College of Radiology Imaging Network)
National Eye Institute Traineeship in Clinical Trials, 1995-1999
Center for Clinical Trials, Johns Hopkins School of Public Health
Travel Award and Finalist, 1998
Society for Clinical Trials Student paper competition, Atlanta, GA
Helen Abby Award for Excellence in Teaching, 1997
Department of Biostatistics, Johns Hopkins School of Public Health
Advising, Mentoring, and Teaching Recognition Award, 1997
Student Assembly, Johns Hopkins School of Public Health
(First student to be awarded an AMTRA)
Affiliations
American Statistical Association
Biometric Society
The Institute of Mathematical Statistics
The Society for Clinical Trials
Teaching
ACRIN Fellows Program
Funded Research
GRANTS:
Active - January 2005 through 2007. Direct Costs: $91,388
Computer-aided Diagnosis Applied to Breast MRI.
NIH R01 (PI, Lehman; Co-PI, Blume)
Active – July 2002 through 2007. Direct Costs: $51,478
Translating ATP III Cholesterol Management Guidelines into Primary Care Practice.
NIH R01 (PI, Eaton; Consultant, Blume)
Completed – July 2001 through 2005. Direct Costs: $123,462
Puberty, Immunity and Malnutrition in S. japonicum.
NIH R01-AI48123 (PI, McGarvey/Kurtis; Co-PI, Blume)
CONTRACTS:
Active – July 2002 through 2008. Direct Costs: $930,173
AVON foundation and NCI (by way of ACRIN)
Subcontract (PI, Gatsonis; Co-PI, Blume)
Completed – August 1999 through 2005. Direct Costs: $188,846
Women and Infants' Hospital, Division of Research
Subcontract (PI, Blume)
Web Links
Curriculum Vitae
Download Jeffrey Blume's Curriculum Vitae in PDF Format
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